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We were called to reports of a collision between a car and a motorbike, at around 6.30pm on Saturday, April 20 on the A53 near Buxton.
The incident took place at the Dalehead junction on Axe Edge Moor, and involved a silver Skoda Fabia and a blue Yamaha XT bike.
The injured biker, a 55 year old man, was taken to hospital for treatment.
Officers are keen to trace the Skoda, registration MD04 VVK, which failed to stop at the scene.
It had reportedly been sold at Buxton Raceway earlier in the day, and is understood to be in the Stockport area.
If you witnessed the collision, or have any information regarding the whereabouts of the Skoda Fabia or its driver, please get in touch using one of the following non-emergency contact methods.
Please quote the reference number 19000201256 and the name of the officer in the case, PC Jack Barlow, in any correspondence.
You can also call Crimestoppers anonymously on 0800 555 111.
Please note in the event of an emergency you should always call 999.