The force was called to reports that a man had been found with serious injuries on a footpath off Station Approach in Derby city centre at 6.40am today (12 February).
The man, who is in 40s, was pronounced dead at the scene.
There is not believed to be any suspicious circumstances at this time and his family have been made aware.
Enquiries are ongoing and officers are keen to speak to anyone who may have been in the area, in particular any drivers that may have captured any dashcam footage on Pride Parkway between 9pm last night (Sunday 11 February) and 6.40am today.
Anyone with information is asked to contact the force using reference 24000087382 and the below methods: